| basic FUNCTION
| calcium sensor for transmitter release at the central synapse, involved in exocytosis and endocytosis |
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serves as a Ca(2+) sensor in the release of neurotransmitters and hormone |
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may be involved in the control of synaptic neuropeptide release or some other form of Ca2+-induced exocytosis |
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major Ca2+ sensor for exocytosis in chromaffin cells, which, together with synaptotagmin-1, mediates almost all of the Ca2+ triggering of exocytosis in these cells |
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functioning by binding to Ca2+ and, thus in this sense, is a Ca2+ sensor |
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acting to trigger exocytosis in a manner similar to synaptotagmin-1, by binding to phospholipids and SNARE proteins |
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plays an important role in bone remodeling and homeostasis by modulating secretory pathways functionally important in osteoclasts and osteoblasts  |
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principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas |
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Ca(2+) sensor of dense core vesicles fusion machinery ( |
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with SYTL5, are positive regulators of chemotaxis |
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Ca(2+) sensor that regulates lysosome exocytosis and plasma membrane repair |
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controls fusion pore dynamics during exocytosis via a push-and-pull mechanism in which Ca2+ binding to both C2 domains promotes fusion pore opening, but the C2B domain is selectively essential for continuous expansion of an otherwise unstable fusion pore |
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