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FLASH GENE
Symbol SV2A contributors: mlc - updated : 20-11-2007
HGNC name synaptic vesicle glycoprotein 2A
HGNC id 20566
Location 1q21.2      Physical location : 149.874.875 - 149.889.434
Synonym symbol(s) SV2, KIAA0736
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     13 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
13 - 4066 - 742 - Gregory (2006)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   moderately
Digestivesalivary gland   highly
Nervousbrain   predominantly
Reproductivefemale systemovary  highly
 male systemtestis  highly
Respiratorylung   highly
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
twelve transmembrane domains
conjugated GlycoP
HOMOLOGY
interspecies homolog to Drosophila CG3168
Homologene
FAMILY
CATEGORY secretory , transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
intracellular,cytoplasm,cytosolic,vesicle
text synaptic vesicle
basic FUNCTION synaptic vesicle transmembrane proteoglycan, involved in the control of exocytosis
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS nervous system , exocytosis transport
PATHWAY
metabolism
signaling neurotransmission
a component
INTERACTION
DNA
RNA
small molecule
protein interaction between purified SV2 and laminin-1, a laminin isoform with a similar structure
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS