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FLASH GENE
Symbol SUMF2 contributors: - updated : 02-06-2005
HGNC name sulfatase modifying factor 2
HGNC id 20415
Location 7q11.1      Physical location : 56.131.916 - 56.148.364
DNA
TYPE functioning gene
STRUCTURE 16.00 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  predominantly
 stomach   highly
Lymphoid/Immunethymus   highly
Reproductivefemale systemuteruscervix moderately
 female systembreastmammary gland moderately
Skin/Tegumentskin   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a tripartite domain structure
conjugated GlycoP
HOMOLOGY
interspecies ortholog to murine Sumf2
intraspecies paralog to SUMF1
Homologene
FAMILY sulfatase modifying factor family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,lumen
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION
  • may convert newly synthesized inactive sulfatases to their active form by modifying an active site cysteine residue to 3-oxoalanine
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS