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FLASH GENE
Symbol SULT1C2 contributors: - updated : 23-07-2007
HGNC name sulfotransferase family, cytosolic, 1C, member 2
HGNC id 11456
Location 2q11.1-q11.2      Physical location : 108.905.094 - 108.926.370
Synonym name
  • sulfotransferase family, cytosolic, 1C, member 1
  • sulfotransferase 1C1
  • Synonym symbol(s) SULT1C, ST1C1, SULT1C1, ST1C2, humSULTC2
    EC.number 2.8.2.-
    DNA
    TYPE functioning gene
    STRUCTURE 21.00 kb     9 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    ECRG4 2q12.2 esophageal cancer related gene 4 protein UXS1 2q12.1 UDP-glucuronate decarboxylase 1 LOC391415 2 similar to ribosomal protein S21; 40S ribosomal protein S21 LOC391416 2 similar to hypothetical protein MGC4614 LOC389016 2 similar to RAN-binding protein 2-like 1 isoform 1; sperm membrane protein BS-63; RAN-binding protein 2-like 1 LOC391417 2 similar to anaphase-promoting complex 1 (meiotic checkpoint regulator) CD8B2 2q12 CD8 antigen, beta polypeptide 2, pseudogene (p37) LOC389017 2 similar to Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu) LOC389018 2 similar to Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu) ST6GalII 2q11.2-q12.1 beta-galactoside alpha-2,6-sialyltransferase II LOC339819 2q12.3 similar to protein phosphatase 1, regulatory (inhibitor) subunit 2 DKFZp686P0288 2q12.3 similar to Ran-binding protein 2 SLC5A7 2q12 solute carrier family 5 (choline transporter), member 7 LOC391418 2 similar to phenol sulfotransferase SULT1C1 2q11.1-q11.2 sulfotransferase family, cytosolic, 1C, member 1 LOC391419 2 similar to sulfotransferase 1C SULT1C2 2q11.2 sulfotransferase family, cytosolic, 1C, member 2 GCC2 2q12-q13 GRIP and coiled-coil domain-containing 2 MGC10701 2q12.3 hypothetical protein MGC10701 LIMS1 2q12 LIM and senescent cell antigen-like domains 1 LOC391420 2 similar to 60S ribosomal protein L10 (QM protein) (Tumor suppressor QM) (Laminin receptor homolog) RANBP2 2q11-q13 RAN binding protein 2 FLJ32745 2q12.3 hypothetical protein FLJ32745 EDAR 2q11-q13 ectodysplasin 1, anhidrotic receptor LOC389019 2 LOC389019 FLJ20019 2q13 hypothetical protein FLJ20019 FLJ00204 2q13 FLJ00204 protein SEPT10 2q13 septin 10 FLJ21870 2q13 hypothetical protein FLJ21870 LOC391421 2 similar to Ribosome biogenesis protein BMS1 homolog LOC391422 2 similar to ribosomal protein L22 RANBP2L1 2q12.3 RAN binding protein 2-like 1 LOC339692 2q13 hypothetical protein LOC339692 GPAA1P1 2q12-q14 glycosylphosphatidylinositol anchor attachment 1 pseudogene 1 LOC391423 2 similar to zinc finger protein 499 LOC343938 2q13 similar to zinc finger protein BENE 2q13 BENE protein NPHP1 2q12-q13 nephronophthisis 1 (juvenile) LOC205251 2q13 hypothetical protein LOC205251 FLJ38359 2q13 hypothetical protein FLJ38359
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 2799 34 296 - Freimuth
    - - 2832 - 307 - Freimuth
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus   highly
     salivary gland   highly
    Endocrineparathyroid   highly
    Nervousspinal cord   lowly
    Reproductivefemale systemovary  lowly
     male systemprostate   
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    Nervouscentral   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text highly in lung and kidney and lowly in heart
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    sulfotransferase domain
    HOMOLOGY
    interspecies homolog to Drosophila CG5428
    homolog to C.elegans T15D6.1
    Homologene
    FAMILY sulfotransferase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • transfer the sulpho moiety from the cofactor 5'-phosphoadenosine-3'-phosphosulphate (PAPS) to nucleophilic groups of xenobiotics and small endogenous compounds (such as hormones and neurotransmitters)
  • involved in the activation of carcinogenic hydroxylamines
  • catalyzing the sulfate conjugation of many drugs, xenobiotic compounds, hormones and neurotransmitters
  • involved in biotransformation of endogenous and exogenous substrates
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS