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FLASH GENE
Symbol SULT1B1 contributors: mct - updated : 13-12-2017
HGNC name sulfotransferase family, cytosolic, 1B, member 1
HGNC id 17845
Location 4q13.3      Physical location : 70.592.687 - 70.626.430
Synonym name thyroid hormone sulfotransferase
Synonym symbol(s) ST1B2, SULT1B2, ST1B1
EC.number 2.8.2-
DNA
TYPE functioning gene
STRUCTURE 33.86 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
UGT2B10 4q13.3 UDP glycosyltransferase 2 family, polypeptide B10 LOC391662 4 similar to UDP-glucuronosyltransferase 2B7 precursor, microsomal (UDPGT) (3,4-catechol estrogen specific) (UDPGTH-2) LOC391663 4 similar to speckle-type POZ protein FLJ21934 4q13.3 hypothetical protein FLJ21934 LOC391664 4 similar to speckle-type POZ protein UGT2B27P 4q13 UDP glycosyltransferase 2 family, polypeptide B27 pseudogene UGT2B26P 4q13 UDP glycosyltransferase 2 family, polypeptide B26 pseudogene UGT2B7 4q13 UDP glycosyltransferase 2 family, polypeptide B7 LOC391665 4 similar to UDP-glucuronosyltransferase 2A1 precursor LOC391666 4 similar to RSDK2559 UGT2B11 4q13.3 UDP glycosyltransferase 2 family, polypeptide B11 LOC391667 4 similar to RSDK2559 UGT2B28 4q13.3 UDP glycosyltransferase 2 family, polypeptide B28 LOC391668 4 similar to RSDK2559 UGT2B25P 4q13 UDP glycosyltransferase 2 family, polypeptide B25 pseudogene UGT2B24P 4q13 UDP glycosyltransferase 2 family, polypeptide B24 pseudogene LOC389209 4 LOC389209 UGT2B4 4q13 UDP glycosyltransferase 2 family, polypeptide B4 UGT2A1 4q13 UDP glycosyltransferase 2 family, polypeptide A1 SULT1B1 4q13 sulfotransferase family, cytosolic, 1B, member 1 SULT1D1P 4q13.3 sulfotransferase family, cytosolic, 1B, member 1 STE 4q13.1 sulfotransferase, estrogen-preferring CSN1S1 4q21.1 casein alpha s1 CSN2 4q13.1-q21.1 casein beta STATH 4q11-q13 statherin HTN3 4q13 histatin 3 HTN1 4q13.3 histatin 1 FLJ20513 C4orf7 4q13 chromosome 4 open reading frame 7 CSN3 4q13.1-q21.1 casein kappa NYD-SP26 4q13.3 testis development protein NYD-SP26 PROL5 4q13.2 proline rich 5 (salivary) PROL3 4q13.3 proline rich 3 PROL1 4q13.2 proline rich 1 MUC7 4q13-q21 mucin 7, salivary
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 1320 - 296 - 1998 9463486
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver     Mus musculus
Nervousbrain     Mus musculus
Urinarykidneynephronrenal capsuleglomerulus  Mus musculus
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Urinarypodocyte Mus musculus
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
interspecies homolog to murine Sult1d1
intraspecies homolog to SULT1
Homologene
FAMILY sulfotransferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,Golgi
intracellular,cytoplasm,cytosolic
text
  • detected in the kidney exclusively in the Golgi apparatus of the podocyte
  • basic FUNCTION
  • catalyzing the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds
  • functional role of ST1B subfamily of sulfotransferases (STs) in xanthurenic acid sulfate formation in the body
  • may be involved in the sulfonylation of podocyte protein podocalyxin
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS