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FLASH GENE
Symbol SULT1A3 contributors: npt/ - updated : 05-04-2006
HGNC name sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
HGNC id 11455
Location 16p11.2      Physical location : 29.467.126 - 30.215.649
Synonym name
  • monoamine-sulfating phenol sulfotransferase
  • thermolabile phenol sulfotransferase
  • placental estrogen sulfotransferase
  • sulfotransferase 1A3/1A4
  • thermolabile (monoamine, M form) phenol sulfotransferase
  • Synonym symbol(s) STEA, TLPST, STM, HAST, HAST3, M-PST, MGC117469
    EC.number 2.8.2.1
    DNA
    TYPE functioning gene
    SPECIAL FEATURE overlapping
    text overlap with exons of a gene that encodes a protein containing GIY-YIG domains (GIYD1)
    STRUCTURE 9.91 kb     10 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 1604 34.2 295 - Pai (2003)
    8 - 1421 - 295 - Pai (2003)
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticspleen    
    Digestiveintestinelarge intestinecolon  
     intestinesmall intestine   
     liver    
    Nervousbrain    
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoietic    
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticleukocyte
    cell lineage
    cell lines osteosarcoma cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • the LDQKW sequence motif
  • mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to C.elegans y67a10a-4
    Homologene
    FAMILY
  • sulfotransferase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • catalyzing the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamin, serotonin) phenolic and catechol drugs
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS