basic FUNCTION
| probable pseudophosphatase |
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seems to play a role in spermiogenesis |
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STYX is an important regulator of ERK1/2 signaling critical for cell migration and PC12 cell differentiation |
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STYX and MAPK-STYX (STYXL1), are integral signaling molecules in regulating pathways involved in neuronal developmental processes such as neurite outgrowth |
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STYX acts as a nuclear anchor for MAPKs, affecting their nucleo-cytoplasmic shuttling |
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STYX plays an oncogenic role by inhibiting FBXW7 |
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very specific role of STYX and STYXL1 for each pseudophosphatase, further highlighting the relevance of these atypical members of DUSP as signaling regulators |