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FLASH GENE
Symbol STRC contributors: - updated : 05-05-2007
HGNC name stereocilin
HGNC id 16035
Corresponding disease
DFNB16 neurosensory deafness 16
DIS deafness-infertility syndrome
Location 15q15.3      Physical location : 43.891.761 - 43.910.998
Synonym symbol(s) DFNB16
DNA
TYPE functioning gene
SPECIAL FEATURE
text tandemly duplicated
STRUCTURE 19.00 kb     29 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach   moderately
Hearing/Equilibriumearinnercochlea  
Reproductivemale systemtestis  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsensorystato-auditory  
cells
SystemCellPubmedSpeciesStageRna symbol
Hearing / Equilibriumcochlea cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a putative signal peptide
  • several hydrophobic segments
    • conjugated GlycoP
    isoforms Precursor
    HOMOLOGY
    interspecies ortholog to murine Strc
    homolog to dog LOC478278
    Homologene
    FAMILY stereocilin family
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling sensory transduction/hearing
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DFNB16 , DIS
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS