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FLASH GENE

Symbol

STAC

contributors: npt/ - updated : 18-03-2006

HGNC name	SH3 and cysteine rich domain
HGNC id	11353

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3p22.3      Physical location : 36.422.096 - 36.589.496
Synonym name	src homology three (SH3) and cysteine rich domain
Synonym symbol(s)	STAC1, FLJ32331

DNA

TYPE	functioning gene
STRUCTURE	167.40 kb     14 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

Map	pter - D3S512 - D3S1277 - D3S1768 - D3S3124 - D3S1612 - D3S3987 - D3S2447 - D3S3718 - D3S2369 - D3S3042 - D3S2971 - D3S1561 - D3S1611 - D3S3623 - D3S3382 - D3S1298 - cen
Authors	Petek (99)

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed STAC 14 - 2963 44.5 402 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain diencephalon hypothalamus   predominantly   brain hindbrain cerebellum

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Nervous peripherous

cells

System Cell Pubmed Species Stage Rna symbol Nervous neuron

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a cysteine-rich and a SH3 domains
	a phorbol ester/diacylglycerol binding domain
	zinc dependent (Dag binding domain)

HOMOLOGY

interspecies

homolog to murine Stac

Homologene

FAMILY

CATEGORY

signaling neurotransmitter

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

signal transduction

neuron-specific

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS