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FLASH GENE
Symbol ST7L contributors: - updated : 10-01-2006
HGNC name suppression of tumorigenicity 7 like
HGNC id 18441
Location 1p13      Physical location : 113.066.141 - 113.162.040
Synonym symbol(s) ST7R, STLR, FLJ11657, FLJ20284
DNA
TYPE like-sequence
SPECIAL FEATURE component of a cluster, tail to tail
text in tail-to-tail manner with an interval of less than 5.0-kb. ST7L-WNT2B
STRUCTURE 84.00 kb     15 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 4552 - 575 - Katoh
- splicing 4502 - 558 - Katoh
missing an internal region,
- splicing 4459 - 544 - Katoh
missing an internal region
- splicing 2142 - 555 - Katoh
a distinct and shorter C-terminus,
- splicing 4508 - 555 - Katoh
a distinct C-terminus compared to isoform 1
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousnervecranial nerveoptic nerve  
Reproductivemale systemprostate   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text umbilical cord blood
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
leucine zipper domain and three tyrosine-phosphorylation sites
HOMOLOGY
Homologene
FAMILY
CATEGORY tumor suppressor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
intracellular,nucleus
basic FUNCTION tumor suppressor gene
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in gastric cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS