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FLASH GENE
Symbol ST6GALNAC1 contributors: - updated : 24-05-2006
HGNC name ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
HGNC id 23614
Location 17q25.1      Physical location : 74.620.846 - 74.639.894
Synonym name sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) A
Synonym symbol(s) SIAT7A, HSY11339, ST6GalNAc-I
EC.number 2.4.99.3
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2437 68 600 - Ikehara
  • an active enzyme
  • - splicing 2230 - - - Ikehara
  • an inactive enzyme
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
     stomach   highly
    Lymphoid/Immunespleen   moderately
    Reproductivefemale systemuteruscervix predominantly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscular    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine St6galnac1
    ortholog to murine Siat7a
    ortholog to chimpanzee sia7a
    Homologene
    FAMILY glycosyltransferase 29 family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    text type II membrane protein
    basic FUNCTION
  • involved in glycosylation of proteins
  • major Sialyl-Tn synthase and playing a role in carcinogenesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS