Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
| deletion
|  
|  
|
in B cell prolymphocytic leukemia, colorectal carcinoma, cutaneous malignant melanoma, chronic lymphocytic leukemia, mantle cell lymphoma, childhood acute lymphoblastic leukemia, B cell chronic lymphocytic leukemia, T prolymphocytic leukemia | tumoral
|  
| LOH
|  
|  
|
in lung cancer, ovarian cancer, breast carcinoma early onset and reduced survival, cervical, esophageal squamous cell carcinoma, paragangliomas of the head and neck, ataxia telangiectasia, Cowden disease, | tumoral
|  
| LOH
|  
|  
|
in adenocarcinoma of the stomach, nasopharyngeal carcinoma, lung adenocarcinoma, malignant melanoma (LOH often including ATM locus, see symbol), see also LPD, LOH11CR2A, PGL1, MTCL | tumoral
|  
| LOH
|  
|  
|
in pheochromocytoma and paraganglioma (Sun 2007) | |