Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SSH2 contributors: - updated : 16-12-2004
HGNC name slingshot 2
HGNC id 30580
Location 17q11.2      Physical location : 27.952.964 - 28.257.018
Synonym symbol(s) SSH-2, KIAA1725
DNA
TYPE functioning gene
STRUCTURE 304.00 kb     19 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
SDF2 17q11.2 stromal cell-derived factor 2 SUPT6H 17q11.2 suppressor of Ty 6 homolog (S. cerevisiae) MGC39650 17q11.2 hypothetical protein MGC39650 RAB34 17q11.1 RAB34, member RAS oncogene family RPL23A 17q11 ribosomal protein L23a LOC116238 17q11.2 hypothetical protein BC014072 NEK8 17q11.1 NIMA (never in mitosis gene a)- related kinase 8 TRAF4 17q11-q12 TNF receptor-associated factor 4 FLJ10700 17q11.2 hypothetical protein FLJ10700 ERAL1 17q11.2 Era G-protein-like 1 (E. coli) FLOT2 17q11.2-q12 flotillin 2 MGC23280 17q11.2 hypothetical protein MGC23280 PHF12 17q11.2 PHD finger protein 12 SEZ6 17q11.2 seizure related 6 homolog (mouse) LOC342659 17q11.2 similar to NADH-ubiquinone oxidoreductase 15 kDa subunit (Complex I-15 kDa) (CI-15 kDa) PIPOX 17q11.2 pipecolic acid oxidase TIAF1 17q11.1-q11.2 TGFB1-induced anti-apoptotic factor 1 LOC390783 17 hypothetical gene supported by U02680; NM_002822 CRYBA1 17q11.2-q12 crystallin, beta A1 182-FIP 17q11.2 82-kD FMRP Interacting Protein KIAA1361 17q11.2 serine/threonine protein kinase TAO1 homolog LOC116236 17q11.2 hypothetical protein LOC116236 LOC90313 17q11.2 hypothetical protein BC004507 GIT1 17p11.2 G protein-coupled receptor kinase-interactor 1 FLJ25555 17q11.2 hypothetical protein FLJ25555 FLJ14871 17q11.2 hypothetical protein FLJ14871 SSH2 17q11.2 slingshot 2 FLJ46247 17q11.2 FLJ46247 protein DKFZP434K1421 17q11.2 hypothetical protein DKFZp434K1421 SLC6A4 17q11.2 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 BLMH 17q11.2 bleomycin hydrolase LOC388364 17 similar to AWKS9372 CPD 17q11.2 carboxypeptidase D
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1796 - 440 - Niwa
- - 1008 - 195 - Niwa
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunespleen    
 thymus    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoietic    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a phosphatase domain distantly related to those of the family of mitogen-activated protein kinase phosphatases
HOMOLOGY
Homologene
FAMILY SSH gene family
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
intracellular,nucleus
basic FUNCTION
  • regulating mitogenic signal transduction by dephosphorylating both THR and TYR residues on map kinases ERK1 and ERK2
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS