basic FUNCTION
| binds and stabilizes DNA single strand for replication |
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with POLDIP2 is involved in the processes of mitochondrial fission and fusion, respectively |
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playing a role in cell survival |
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SSBP1 and SSBP2 form two separate complexes with similar structures, and both are required for efficient homologous recombination (HR)-dependent repair of DSBs and ATM-dependent signaling pathways |
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plays an important role in the DNA damage response and maintenance of genomic stability |
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plays important roles in DNA replication, recombination and repair through binding to single-stranded DNA |
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required for maintenance of mitochondrial DNA and 7S DNA but is not required for mitochondrial nucleoid organisation |
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may positively modulate CDKN1A to regulate cell cycle progression and DNA damage response |