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FLASH GENE
Symbol SRRM1 contributors: npt/ - updated : 20-02-2013
HGNC name serine/arginine repetitive matrix 1
HGNC id 16638
Location 1p36.11      Physical location : 24.969.593 - 24.999.771
Synonym name
  • Ser/Arg-related nuclear matrix protein
  • plenty of prolines 101-like
  • Synonym symbol(s) SRM160, POP101, MGC39488, 160-KD
    DNA
    TYPE functioning gene
    STRUCTURE 30.18 kb     17 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    17 - 3952 102.3 904 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • PWI domain
  • multiple putative phosphorylation sites
  • SH3-binding motifs
  • HOMOLOGY
    interspecies homolog to murine Srrm1
    homolog to Drosophila cg3961
    homolog to C.elegans y65b4bl.5
    Homologene
    FAMILY
  • splicing factor SR family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
    text nuclear matrix protein
    basic FUNCTION
  • required for splicing of specific pre-mRNAs
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the SRm 160/300 complex of nuclear matrix proteins
  • spliceosomal subunit
  • INTERACTION
    DNA
    RNA pre-mRNA dependent on RNU1A and stabilized by RNU2
    small molecule
    protein
  • SRRM2
  • SFRS5
  • SFRS4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS