basic FUNCTION
| highly specific for the serine/arginine repeats, modulating the affinity between RS domain containing proteins and regulating the cellular distribution of their substrates |
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cell cycle regulator |
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controling localization of splicing factors |
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playing a role in the condensation of sperm chromatin |
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may play an important role in linking signaling to RNA metabolism in higher eukaryotic cells  |
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phosphorylate serine/arginine (SR) domain-containing proteins in nuclear speckles and mediate the pre-mRNA splicing  |
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involved in the molecular chaperone system that has been implicated in numerous signal transduction pathways and provide mechanistic insights into complex regulation of SR protein phosphorylation and alternative splicing in response to developmental cues and cellular signaling  |
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in addition to phosphorylating SR proteins and regulating pre-mRNA splicing, SRPK1 and SRPK2 also play an important role in cell proliferation and apoptosis  |