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FLASH GENE
Symbol SPRR2G contributors: - updated : 08-04-2006
HGNC name small proline-rich protein 2G
HGNC id 11267
Location 1q21-q22      Physical location : 153.122.058 - 153.123.427
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text clustered in the epidermal differentiation complex (EDC)
STRUCTURE 1.00 kb     2 Exon(s)
text structure open reading frame in a single exon
MAPPING cloned Y linked N status confirmed
Map cen - SPRR4 - SPRR1A - SPRR3 - SPRR1B - SPRR2D - SPRR2A - SPRR2B - SPRR2E - SPRR2F - SPRR2C - SPRR2G - tel
Authors Cabral et al.(01)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx    
Nervousbrain    
cell lineage precursor of cornified cell envelope
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a central segment built up from nine octapeptide repeats,*K*PEP*
mono polymer heteromer , tetramer
HOMOLOGY
Homologene
FAMILY potassium channel family, a (shaker) subfamily
CATEGORY transport channel
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton
text cornifin
basic FUNCTION
  • mediating the voltage-dependent potassium ion permeability of excitable membranes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • clustered in the epidermal differentiation complex (EDC)
  • heterotetramer of potassium channel proteins
    • INTERACTION
    DNA
    RNA
    small molecule
    protein binding PDZ domains of DLG1, DLG2 and DLG4
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS