| Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
| HGNC | UniGene | Nucleotide | OMIM | UCSC |
| Home Page |
| FLASH GENE |
| Symbol | SPRR2B | contributors: - updated : 12-05-2006 |
| HGNC name | small proline-rich protein 2B |
| HGNC id | 11262 |
|
|
| Location | 1q21 Physical location : 153.042.719 - 153.044.084 |
| DNA |
| TYPE | functioning gene |
| SPECIAL FEATURE | component of a cluster |
| text | clustered in the epidermal differentiation complex (EDC) |
| STRUCTURE | 1.00 kb 2 Exon(s) |
|
| Genomic sequence alignment details |
|---|
| 10 Kb 5' upstream gene genomic sequence study |
| text structure | open reading frame in a single exon |
| MAPPING | cloned | Y | linked | N | status | confirmed |
| Map | cen - SPRR4 - SPRR1A - SPRR3 - SPRR1B - SPRR2D - SPRR2A - SPRR2B - SPRR2E - SPRR2F - SPRR2C - SPRR2G - tel |
| Authors | Cabral et al.(01) |
| RNA |
| TRANSCRIPTS | type | messenger |
|---|
| EXPRESSION |
| Type | restricted |
| constitutive of |
| expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
| organ(s) |
|
| tissue |
|
| cell lineage | precursor of cornified cell envelope |
cell lines
| fluid/secretion
| |
| at STAGE |
| PROTEIN |
PHYSICAL PROPERTIES
| STRUCTURE
| |
motifs/domains
| a central segment built up from nine octapeptide repeats,*K*PEP* |
| HOMOLOGY |
| Homologene |
| FAMILY | cornifin (SPRR) family |
| CATEGORY | structural protein |
SUBCELLULAR LOCALIZATION
| intracellular |
| intracellular,cytoplasm,cytoskeleton | |
| text | cornifin |
| basic FUNCTION | |
|
| |
| cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase |