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FLASH GENE
Symbol SPP2 contributors: - updated : 20-06-2007
HGNC name secreted phosphoprotein 2, 24kDa
HGNC id 11256
Location 2q37.1      Physical location : 234.959.345 - 234.985.776
Synonym symbol(s) SPP24
DNA
TYPE like-sequence
STRUCTURE 24.00 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
Binding site
text structure potential transcription factor (TF)-binding sites
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
Text liver and kidney
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated PhosphoP
HOMOLOGY
interspecies homolog to bovine spp24
Homologene
FAMILY cystatin family,related sequence
CATEGORY secretory
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION
  • thiol protease inhibitor
  • could coordinate an aspect of bone turnover
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS