Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SPOCK2 contributors: mct - updated : 01-06-2006
HGNC name sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
HGNC id 13564
Location 10pter-q25.3      Physical location : 73.818.792 - 73.848.790
Synonym name KIAA0275 protein
Synonym symbol(s) KIAA0275, testican-2
DNA
TYPE functioning gene
STRUCTURE 29.00 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Spock2
Homologene
FAMILY Testican family proteins
CATEGORY regulatory
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION
  • serine protease inhibitor, that may contribute to glioma invasion by inactivating other testican family members including N-Tes, which all inhibit MT-MMPs
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    calcium Ca2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS