| basic FUNCTION
| important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation |
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playing a role in the physicochemical properties |
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of the T-cell surface and in lectin binding |
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functions potentially as a signaling molecule, sensing extracellular cues and transducing intracellular signals that modulate T-cell function  |
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its overexpression activates TP53 and suppresses colony formation due to induction of apoptosis |
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potential contributor to tumor development and the functional ARF-TP53 pathway is required for the elimination of cells with aberrant CD43 expression |
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highly glycosylated transmembrane protein that regulates T cell activation |
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generally serves as an antiadhesive molecule to attenuate neutrophil-endothelial interactions, but when E-selectin is expressed on endothelial cells, it also plays a proadhesive role as an E-selectin ligand |
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involved in the regulation of lymphocyte adhesion and activation |
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inhibitor for cell adhesion |
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regulates multiple T-cell functions, including T-cell activation, proliferation, apoptosis, and migration |
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SPN movement and regulation of T-cell migration can occur through an ERM-independent, phosphorylation-dependent mechanism |
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transmembrane sialoglycoprotein involved in cell adhesion, differentiation, and apoptosis |
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is the UN1 antigen, peculiarly expressed in fetal tissues and several cancer tissues, including leukemic T cells, breast, and colon carcinomas |
