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FLASH GENE
Symbol SPIN2A contributors: mct - updated : 09-03-2018
HGNC name spindlin family, member 2A
HGNC id 20694
Location Xp11.21      Physical location : 57.162.083 - 57.164.058
Synonym name
  • spindlin-like protein 2
  • protein DXF34
  • centromeric spin2 copy
  • spindlin homolog 2
  • Synonym symbol(s) DXF34, SPIN2, MGC88670, dJ323P24.1, RP3-323P24.2, TDRD25
    DNA
    TYPE functioning gene
    STRUCTURE 4.43 kb     2 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 1351 29 258 - 2017 29061846
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to murine Spin
    Homologene
    FAMILY
  • SPIN/STSY family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • regulating cell cycle progression
  • having an activity related to the inhibition of apoptosis following the removal of essential growth factors
  • CELLULAR PROCESS cell cycle
    cell life, antiapoptosis
    PHYSIOLOGICAL PROCESS
    text cell cycle regulator
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • SPIN2A, 2B, 3, and 4, also bind SPINDOC
  • cell & other
  • binding to the meiotic spindle
  • REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS