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FLASH GENE
Symbol SPATS2L contributors: mct - updated : 25-03-2015
HGNC name spermatogenesis associated, serine-rich 2-like
HGNC id 24574
Location 2q33.1      Physical location : 201.170.603 - 201.346.982
Synonym name
  • DNA polymerase-transactivated protein 6
  • stress granule and nucleolar protein
  • Synonym symbol(s) SGNP, DNAPTP6
    DNA
    TYPE functioning gene
    STRUCTURE 175.38 kb     13 Exon(s)
    MAPPING cloned   linked   status
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    13 - 6407 - 558 - -
    12 - 6346 - 498 - -
    13 - 6275 - 558 - -
    13 - 6335 - 558 - -
    13 - 6285 - 558 - -
    13 - 6135 - 588 - -
    12 - 6128 - 489 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,granule
    intracellular,nucleus,nucleolus
    text
  • under oxidative stress, its nucleolar localization decreases and it rapidly co-localizes with stress granules
  • basic FUNCTION
  • is an essential gene that may be involved in ribosomal biogenesis and translational control in response to oxidative stress
  • may be an important regulator of beta(2)-adrenergic receptor down-regulation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS