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FLASH GENE
Symbol SPATA4 contributors: mct - updated : 08-06-2009
HGNC name spermatogenesis associated 4
HGNC id 17333
Location 4q34.2      Physical location : 177.105.724 - 177.116.822
Synonym name testis and spermatogenesis cell related protein 2
Synonym symbol(s) MGC33432, TSARG2, SPEF1B
DNA
TYPE functioning gene
STRUCTURE 11.10 kb     6 Exon(s)
regulatory sequence Promoter
cytosine-phosphate-guanine/HTF
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 1233 34.6 305 - 2004 15158438
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  highly Homo sapiens
 male systemmale genital tractseminiferous tubule   Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivegerm cell Homo sapiens
ReproductiveLeydig cell Homo sapiens
Reproductivespermatocyte Homo sapiens
Reproductivespermatogonia Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a putative conserved domain DUF1042
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    text usually in the nucleus
    basic FUNCTION
  • may play an important role in the development of cryptorchid testis and be a testis-specific apoptosis candidate oncogene
  • candidate apoptosis-related gene in male germ cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional     --over  
    in cryptorchidism
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS