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FLASH GENE
Symbol SPANXD contributors: mct - updated : 25-08-2007
HGNC name SPANX family, member D
HGNC id 14332
Location Xq27.1      Physical location : 140.785.568 - 140.786.598
Synonym name sperm protein associated with the nucleus, X chromosome, family member D
Synonym symbol(s) MGC119769, SPANX-D
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text
  • five SPANX genes (SPANX-A1, -A2, -B, -C, and -D) encoding sperm proteins associated with the nucleus
  • SPANX genes are >95p100 identical and reside within large segmental duplications (SDs) with a high level of similarity
  • STRUCTURE 1.00 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    BCYRN1P1  brain cytoplasmic RNA 1, pseudogene 1 ATP11C X ATPase, Class VI, type 11C LOC347487 Xq27.1 hypothetical LOC347487 LOC389893 X LOC389893 LOC389894 X hypothetical gene supported by NM_194247 LOC389895 X similar to PRO0149 protein LOC389896 X LOC389896 LOC266694 Xq27.1 embryonic ectoderm development pseudogene SOX3 Xq27.1 SRY (sex determining region Y)-box 3 CDR1 Xq27.1-q27.2 cerebellar degeneration-related protein 1, 34kDa SPANXB1 Xq27.1 SPANX family, member B1 dJ507I15.1 Xq27.1 ribosomal protein L36a pseudogene LDOC1 Xq27.2 leucine zipper, down-regulated in cancer 1 SPANXC Xq27.1 SPANX family, member C NDUFB3P5  NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa pseudogene 5 SPANXA1 Xq27.1 sperm protein associated with the nucleus, X chromosome, family member A1 LOC389897 X hypothetical gene supported by BC042039 SPANXE Xq27.1 SPANX family, member E SPANXD Xq27.1 SPANX family, member D MAGEC3 Xq27.2 melanoma antigen, family C, 3 MAGEC1 Xq26 melanoma antigen, family C, 1 LOC392554 X similar to melanoma antigen, family A, 10; melanoma-associated antigen 10; MAGE-10 antigen LOC392555 X similar to Melanoma-associated antigen E1 (MAGE-E1 antigen) (MAGE-C2 antigen) (Hepatocellular carcinoma-associated antigen 587) (Cancer-testis antigen CT10) LOC139075 Xq27.2 similar to Melanoma-associated antigen E1 (MAGE-E1 antigen) (MAGE-C2 antigen) (Hepatocellular carcinoma-associated antigen 587) (Cancer-testis antigen CT10) MAGEE1 Xq27 melanoma antigen, family E, 1, cancer/testis specific LOC139067 Xq27.3 hypothetical LOC139067
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Reproductivemale systemtestis   
    Skin/Tegumentskin    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductivespermatid
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY SPANX family of cancer/testis-associated genes
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nuclear envelope
    text associated with nuclear envelope of human spermatids and spermatozoa
    basic FUNCTION plays a role during spermiogenesis
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to prostate cancer
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS