Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SPAG17 | contributors: mct - updated : 28-09-2021 |
HGNC name | sperm associated antigen 17 |
HGNC id | 26620 |
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Corresponding disease |
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Location | 1p12 Physical location : 118.496.287 - 118.727.848 | ||
Synonym name | projection protein PF6 | ||
Synonym symbol(s) | PF6, FLJ34497, RP4-776P7.2, FLJ44343, FLJ44353, DKFZp434B0610, FLJ34497, FLJ44343, CT143 |
DNA |
TYPE | functioning gene |
STRUCTURE | 231.64 kb 49 Exon(s) |
regulatory sequence | Promoter |
Binding site | |
text structure | absence of a TATA box, and putative binding sites for several factors implicated in spermatogenesis (CREB/CREM, SOX17 and SPZ1) as well as ciliogenesis (FOXJ1 |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | antigen |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytoskeleton,microtubule | |
intracellular,nucleus | |
text | |
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basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | SPAG17, SPAG6, and SPAG16 form a newly identified network that links together components of the axoneme central apparatus and presumably participates in its dynamic regulation of ciliary and flagellar beat |
INTERACTION |
DNA |
RNA |
small molecule |
protein | associates with SPAG6 |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | SPGF55 |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |