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Symbol SNRPB2 contributors: npt - updated : 03-09-2005
HGNC name small nuclear ribonucleoprotein polypeptide B''
HGNC id 11155
Location 20p12.2-p11.22      Physical location : 16.710.608 - 16.722.417
Synonym name
  • small nuclear ribonucleoprotein polypeptide B2
  • U2 small nuclear ribonucleoprotein B''
  • Synonym symbol(s) MGC24807, MGC45309
    DNA
    TYPE functioning gene
    STRUCTURE 11.41 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    text Variants 1 and 2 encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1281 25.5 225 - -
    - - 1181 25.5 225 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two RNA recognition motifs
  • conjugated RiboP
    HOMOLOGY
    interspecies ortholog to murine Smpb2
    homolog to C.elegans K08D10.3
    Homologene
    FAMILY
  • RRM U1 A/B'' family
  • CATEGORY RNA associated , antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • spliceosome subunit
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • Sn-rnp U2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility systemic lupus erythematosus and rheumatic diseases
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS