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FLASH GENE
Symbol SNRPA contributors: - updated : 18-02-2006
HGNC name small nuclear ribonucleoprotein polypeptide A
HGNC id 11151
Location 19q13.2      Physical location : 41.256.758 - 41.271.296
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Endocrinepancreas   highly
Lymphoid/Immunespleen   highly
 thymus   highly
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
Urinarykidney   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES Hydrophilic
STRUCTURE
motifs/domains
  • two RNA recognition motif (RRM) domains
  • a hydrophilic region
  • an internal sequence duplication
  • a RNP consensus domain common to RNA-binding proteins
  • conjugated RiboP
    HOMOLOGY
    interspecies ortholog to murine Snrpa
    homolog to rattus Rn.9347
    homolog to Xenopus Xl.5225
    homolog to zebrafish Dr.1930
    homolog to C.elegans K08D10.3
    Homologene
    FAMILY U1 A/B" family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION may be involved in coupled pre-mRNA splicing and
    polyadenylation process
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component involved in spliceosome complex
    INTERACTION
    DNA
    RNA binding to stem loop II of U1 snRNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS