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FLASH GENE
Symbol SNRK contributors: npt/ - updated : 29-10-2004
HGNC name SNF related kinase
HGNC id 30598
Location 3p22.1      Physical location : 43.328.003 - 43.392.632
Synonym name
  • sucrose non-fermenting protein (SNF-1)-related kinases
  • SNF-1 related kinase
  • Synonym symbol(s) HSNFRK, FLJ20224, KIAA0096, DKFZp779A1866
    EC.number 2.7.11.1
    DNA
    TYPE functioning gene
    STRUCTURE 64.63 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 5174 - 765 - -
    7 - 5236 - 765 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Nervousbrain    
    Reproductivefemale systemovary   
     male systemprostate   
    Respiratorylung    
    Visualeyeanterior segment   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a serine/threonine kinase catalytic domain
  • a bipartite nuclear targeting signal
  • an ubiquitin-associated domain
  • HOMOLOGY
    interspecies homolog to rat Snrk
    Homologene
    FAMILY
  • protein kinase superfamily
  • CAMK Ser/Thr protein kinase family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in hematopoietic cell proliferation or differentiation
  • CELLULAR PROCESS cell life, differentiation
    cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral       loss of function
    inactivated in renal clear cell carcinomas with poor prognosis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS