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FLASH GENE
Symbol SNORD116@ contributors: mct/npt - updated : 18/10/2008
HGNC name small nucleolar RNA, C/D box 116 cluster
HGNC id 32781
Corresponding disease
PWS Prader-Willi syndrome
Location 15q11.2      Physical location : -
Synonym name
  • Prader-Willi syndrome chromosome region 1
  • Prader-Willi critical region 1
  • C/D box small nucleolar RNA
  • non-coding RNA in the Prader-Willi critical region
    • Synonym symbol(s) PET1, HBII85, HBII-85 snoRNA, PWCR1
    DNA
    TYPE chromosome region
    SPECIAL FEATURE component of a cluster
    text
  • imprinting center, regulatory element organized within local tandem-repeat clusters
  • included in one intron of the SNURF-SNRPN sense / UBE3A antisense transcription unit
    • STRUCTURE 0.00 kb     1 Exon(s)    multiple Copie(s)
    motif
    MAPPING cloned Y linked N status provisional
    Map cen - MKRN3 - NDN - MAGEL2 - SNRPN - PAR5 - SNORD116@ - IPW - PAR1 - UBE3A - qter
    Authors de los Santos (00)
    RNA
    TRANSCRIPTS type untranslated transfer
    text may serve as methylation guidance RNAs in the modification of ribosomal RNA and other small nuclear RNAs
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
     spinal cord    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    IMPRINTING maternally
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY
    SUBCELLULAR LOCALIZATION
    basic FUNCTION role of a particular family of non-coding RNAs, the HBII-85 snoRNA cluster, in energy homeostasis, growth and reproduction (de Smith 2009)
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PWS
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional   deletion    
    associated with hyperphagia, obesity and hypogonadism (De Smith 2009)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS