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FLASH GENE
Symbol SMU1 contributors: mct/npt - updated : 03/12/2008
HGNC name smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
HGNC id 18247
Location 9p12      Physical location : 33.041.849 - 33.076.714
Synonym name
  • brain-enriched WD-repeat protein
  • functional spliceosome-associated protein 57
  • Synonym symbol(s) BWD, SMU-1, FLJ10805, FLJ11970, fSAP57, DKFZp761L0916, FLJ10870, FLJ11970, MGC117363, RP11-54K16.3
    DNA
    TYPE functioning gene
    STRUCTURE 34.86 kb     12 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 7091 57.4 513 - Humphray (2004)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain   predominantly
    Respiratorylung   moderately
     respiratory tractlarynx  highly
    Urinarybladder   moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Nervousperipherous   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • seven WD repeats
  • HOMOLOGY
    interspecies ortholog to rattus Smu-1
    ortholog to murine Smu-1
    homolog to C. elegans smu-1
    Homologene
    FAMILY
  • WD repeat SMU1 family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • may be involved in protein-protein interaction and having a regulatory function in the cell
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS