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FLASH GENE
Symbol SLCO5A1 contributors: mct - updated : 21-08-2010
HGNC name solute carrier organic anion transporter family, member 5A1
HGNC id 19046
Corresponding disease
DEL8q13 chromosome 8q13 microdeletion
Location 8q13.3      Physical location : 70.584.569 - 70.747.299
Synonym name
  • organic anion transporter polypeptide-related protein 4
  • solute carrier family 21 (organic anion transporter), member 15
  • solute carrier family 21 member 15
  • Synonym symbol(s) OATP-J, OATPRP4, SLC21A15, OATP5A1, FLJ39560
    DNA
    TYPE functioning gene
    STRUCTURE 162.63 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    Physical map
    MYBL1 8q22 v-myb myeloblastosis viral oncogene homolog (avian)-like 1 VCIP135 8q13 valosin-containing protein (p97)/p47 complex-interacting protein p135 FLJ11267 8q13.1 hypothetical protein FLJ11267 PTTG3 8q13.1 hypothetical protein FLJ11267 SGKL 8q12.3-q13.1 serum/glucocorticoid regulated kinase-like FLJ25692 8q13.1 hypothetical protein FLJ25692 LOC392228 8 similar to hypothetical class II basic helix-loop-helix protein LOC286187 8q13.1 similar to RIKEN cDNA 1700011J18 COPS5 8q13.1 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) FLJ22490 8q13.1 hypothetical protein FLJ22490 BIG1 8q13 hypothetical protein FLJ22490 LOC389666 8 LOC389666 LOC392229 8 similar to 60S ribosomal protein L17 (L23) (Amino acid starvation-induced protein) (ASI) CPA6 8q12.3 carboxypeptidase A6 FLJ12987 8q13.1 hypothetical protein FLJ12987 VEST1 8q13 vestibule-1 protein LOC389667 8 similar to tropomyosin 4 SULF1 8q13.1 similar to tropomyosin 4 SLCO5A1 8q13.2 solute carrier family 21 (organic anion transporter), member 15 LOC392230 8 similar to BAG-family molecular chaperone regulator-4 (Silencer of death domains) PRDM14 8p21-p12 PR domain containing 14 LOC346990 8q13.2 similar to H2A histone family, member Z NCOA2 8q13.1 nuclear receptor coactivator 2 LOC392231 8 similar to basic transcription factor 3 TRAM1 8q13.1 translocation associated membrane protein 1 CGI-83 LOC389668 8 similar to hypothetical protein FLJ10307 EYA1 8q13.3 eyes absent homolog 1 (Drosophila) MSC 8q21.1-q21.2 musculin (activated B-cell factor-1) TRPA1 8q13 transient receptor potential cation channel, subfamily A, member 1 LOC392232 8 similar to ankyrin-like protein 1; ankyrin-like with transmembrane domains 1 KCNB2 8q13.2 potassium voltage-gated channel, Shab-related subfamily, member 2
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 3806 91.9 848 - 2003 12507753
    9 - 3430 85.8 793 - 2003 12507753
    8 - 3751 73.8 687 - 2003 12507753
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveintestinelarge intestinecolon highly
    Nervousbrain   highly
    Reproductivefemale systemuterus   
     female systembreastmammary gland  
    Respiratoryrespiratory tractlarynx   
    Urinarybladder    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text highly expressed in fetal brain and heart
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • 12 transmembrane domains
  • HOMOLOGY
    Homologene
    FAMILY
  • solute carrier organic anion transporter superfamily
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • mediating the Na(+)-independent transport of organic anions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DEL8q13
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS