Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLCO4C1 contributors: - updated : 18-04-2005
HGNC name solute carrier organic anion transporter family, member 4C1
HGNC id 23612
Location 5q21.2      Physical location : 101.569.693 - 101.632.253
Synonym symbol(s) OATPX, OATP-H, OATP-M1, OATP4C1, PRO2176, SLC21A20
DNA
TYPE functioning gene
STRUCTURE 62.00 kb     13 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
CAST 5q15-q21 calpastatin ARTS-1 5q15 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator LRAP 16 leukocyte-derived arginine aminopeptidase FLJ39485 5q15 hypothetical protein FLJ39485 LNPEP 5q21 leucyl/cystinyl aminopeptidase FLJ25534 5q15 hypothetical protein FLJ25534 RIOK2 5q14 RIO kinase 2 (yeast) LOC391812 5 similar to Dermatomyositis associated with cancer putative autoantigen-1 (DACA-1) LOC391813 5 similar to Zinc finger DHHC domain containing protein 3 (Zinc finger protein 373) (DHHC1 protein) LOC389312 5 similar to Proteasome activator complex subunit 2 (Proteasome activator 28-beta subunit) (PA28beta) (PA28b) (Activator of multicatalytic protease subunit 2) (11S regulator complex beta subunit) (REG-beta) LOC391814 5 similar to cytoplasmic beta-actin MRPS35P2 5q15 mitochondrial ribosomal protein S35 pseudogene 2 LOC285703 5q21.1 similar to C-terminal binding protein 2 isoform 2; ribeye LOC391815 5 similar to ATP-dependent RNA helicase DDX18 (DEAD-box protein 18) (Myc-regulated DEAD-box protein) (MrDb) FLJ90406 CHD1 5q15-q21 chromodomain helicase DNA binding protein 1 LOC389313 5 LOC389313 LOC256055 5q21.1 similar to Beta-glucuronidase precursor (Beta-G1) LOC285706 5q21.1 cytokine receptor-like factor 3 pseudogene LOC389314 5 similar to NADH dehydrogenase subunit 5 LOC389315 5 LOC389315 UNQ1912 5q21.1 HGS_RE408 SIAT8D 5p21 sialyltransferase 8D (alpha-2, 8-polysialyltransferase) SLCO4C1 5q21.2 solute carrier organic anion transporter family, member 4C1 SLCO6A1 5q21.2 solute carrier organic anion transporter family, member 6A1 PAM 5q15 peptidylglycine alpha-amidating monooxygenase LOC134505 5q21.2 similar to eukaryotic translation initiation factor 3 subunit k; muscle specific gene FLJ20125 5q21.2 hypothetical protein FLJ20125 KIAA0433 5q21-q23 hypothetical protein FLJ20125 LOC90355 5q21.2 hypothetical gene supported by AF038182; BC009203 LOC345761 5q21.3 similar to 2610034M16Rik protein NUDT12 5q15 nudix (nucleoside diphosphate linked moiety X)-type motif 12 RAB9P1 5q14.3-q15 RAB9, member RAS oncogene family, pseudogene 1 LOC345571 5q21.3 similar to rap2 interacting protein x LOC391817 5 similar to protease (prosome, macropain) 26S subunit, ATPase 1 EFNA5 5q21 ephrin-A5
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Respiratorylung    
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialabsorptive excretoryglomerular epithelium  
Epithelialabsorptive excretoryrenal tubular epithelium  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text liver, kidney
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • twelve transmembrane domains with intracellular N and C termini
  • two potential ATP-binding Walker A motifs in the cytosolic portion between transmembrane domains 6 and 7
  • four putative N-glycosylation sites in the extracellular loops
  • five potential cytosolic phosphorylation sites
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • transporting the cardiac glycosides digoxin and ouabain, the thyroid hormones triiodothyronine and thyroxine, cAMP, and methotrexate in a sodium-independent manner
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS