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FLASH GENE
Symbol SLCO4A1 contributors: - updated : 12-05-2007
HGNC name solute carrier organic anion transporter family, member 4A1
HGNC id 10953
Location 20q13.2-q13.3      Physical location : 61.273.796 - 61.303.647
Synonym name
  • organic anion transporter 1
  • solute carrier family 21 (organic anion transporter), member 12
  • colon organic anion transporter
  • Synonym symbol(s) OATPE, SLC21A12, OATP4A1, OATPRP1, POAT
    DNA
    TYPE functioning gene
    STRUCTURE 29.00 kb     12 Exon(s)
    regulatory sequence
    MAPPING cloned Y linked N status provisional
    Physical map
    ADRM1 20q13.33 adhesion regulating molecule 1 LAMA5 20q13.2-q13.3 laminin, alpha 5 RPS21 20q13.3 ribosomal protein S21 C20orf150 20q13.33 chromosome 20 open reading frame 150 C20orf151 20q13.33 chromosome 20 open reading frame 151 GATA5 20q11.21-q11.22 GATA binding protein 5 RPL7P3 20q13.33 ribosomal protein L7 pseudogene 3 C20orf166 20q13.33 chromosome 20 open reading frame 166 FLJ30313 20q13.33 hypothetical protein FLJ30313 LOC388805 20 LOC388805 FLJ32154 20q13.33 hypothetical protein FLJ32154 SLCO4A1 20q13.33 solute carrier organic anion transporter family, member 4A1 NTSR1 20q13 neurotensin receptor 1 (high affinity) LOC391261 20 similar to putative glycine-rich protein C20orf20 20q13.33 chromosome 20 open reading frame 20 OGFR 20q13 opioid growth factor receptor COL9A3 20q13.3 collagen, type IX, alpha 3 TCFL5 20q13.3 transcription factor-like 5 (basic helix-loop-helix) C20orf143 20q13.33 chromosome 20 open reading frame 143 ARF4P2 20q13.33 ADP-ribosylation factor 4 pseudogene 2 C20orf158 20q13.33 chromosome 20 open reading frame 158 DATF1 20q13.33 death associated transcription factor 1 C20orf11 20q13.33 chromosome 20 open reading frame 11 C20orf59 20q13.33 chromosome 20 open reading frame 59 LOC388806 20 hypothetical gene supported by AK128846 LOC343565 20q13.33 similar to VsaA -like protein C20orf51 20q13.33 chromosome 20 open reading frame 51
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
    Lymphoid/Immunelymph node    
     thymus    
    Reproductivemale systemprostate  highly
    Urinarykidney    
    Visualeye   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • twelve transmembrane domains
  • N glycosylation sites
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY SLC21A superfamily of solute carriers
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • transport of 3(H)estrone-3-sulfate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS active transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein bound predominantly to the first and third PDZ binding domains of PDZK1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS