Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SLCO2A1 | contributors: shn - updated : 07-10-2019 |
HGNC name | solute carrier organic anion transporter family, member 2A1 |
HGNC id | 10955 |
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Corresponding disease |
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Location | 3q22.2 Physical location : 133.651.541 - 133.748.920 | ||||
Synonym name | |||||
prostaglandin transporter | |||||
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Synonym symbol(s) | PGT, OATP2A1, SLC21A2, MATR1, PHOAR2 |
DNA |
TYPE | functioning gene |
STRUCTURE | 97.38 kb 14 Exon(s) |
regulatory sequence | Promoter (TATA box) | |
Binding site cAMP | ||
motif
text structure
| two Sp.1 sequences | |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D3S3713 - D3S3657 - SLCO2A1 - D3S3684 - D3S3637 - qter |
RNA |
TRANSCRIPTS | type | messenger |
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text | several transcripts (Lu) |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal, pregnancy |
Text | placenta, brain, lung, liver, kidney |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP |
HOMOLOGY |
interspecies | ortholog to Slco2a1, Rattus norvegicus |
ortholog to slco2a1, Danio rerio | |
ortholog to SLCO2A1, Pan troglodytes | |
ortholog to slco2a1, Mus musculus |
Homologene |
FAMILY | organic anion transporting polypeptide (OATP) family |
CATEGORY | transport carrier |
SUBCELLULAR LOCALIZATION | plasma membrane |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | active transport |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | PHTO2 , CEAS |
Susceptibility | to digital clubbing and early-onset colon neoplasia |
Variant & Polymorphism other | |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |