Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLC9A7 contributors: mct - updated : 19-02-2018
HGNC name solute carrier family 9 (sodium/hydrogen exchanger), isoform 7
HGNC id 17123
Location Xp11.3      Physical location : 46.466.372 - 46.618.472
Synonym name non selective sodium potassium/proton exchanger
Synonym symbol(s) NHE7
DNA
TYPE functioning gene
STRUCTURE 152.00 kb     17 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map pter - DXS8026 - DXS8083 - DXS1446 - DXS7804 - DXS1408 - DXS1264 - DXS1055 - DXS1290 - DXS1003 - SLC9A7 - DXS1146 - RP2 RP2 - DXS1266 - PHF16 - RGN - RBM10 - INE1 - DXS7590 - PCTK1 - UBE1 - USP11 - ZNF157 - DXS337 - ZNF41 - ARAF - TIMP1 - SYN1 - PFC - ELK1 - DXS426 - UXT - cen
Authors Thiselton (02)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
17 - 2200 - 725 - Lin(2005)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas   highly
Nervousbrainbasal nucleiputamen highly
 brainforebraincerebral lobeoccipitalhighly
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • twelve N terminal alpha-helical hydrophobic membrane-spanning segments
  • a C terminal hydrophilic cytoplasmic tail
  • HOMOLOGY
    interspecies homolog to C.elegans R166.5
    intraspecies homolog to NHE6
    Homologene
    FAMILY
    CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    text
  • seem exclusively localized in intracellular organelles such as trans-Golgi network
  • basic FUNCTION playing a role in maintaining the cation homeostasis and function of the trans-Golgi network
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interaction with RACK1 through a conserved Region in the C Terminus
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS