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FLASH GENE
Symbol SLC35D2 contributors: mlc - updated : 25-01-2006
HGNC name solute carrier family 35, member D2
HGNC id 20799
Location 9q22.33      Physical location : 99.082.988 - 99.145.992
Synonym name
  • UDP-glucuronic acid UDP-N-acetylgalactosamine dual transporter
  • fringe connection
  • nucleotide-sugar transporter similar to C. elegans sqv-7
  • nucleotide sugar transporter UGTrel8
  • Synonym symbol(s) SQV7L, UGTrel8, hfrc, HFRC1, MGC117215, MGC142139
    DNA
    TYPE functioning gene
    STRUCTURE 62.00 kb     12 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveesophagus    
     liver    
    Reproductivefemale systemovary   
     male systemtestis   
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text pancreas
    PROTEIN
    PHYSICAL PROPERTIES Hydrophobic
    STRUCTURE
    motifs/domains
    ten putative trasmembrane helices
    HOMOLOGY
    Homologene
    FAMILY SLC35 nucleotide sugar transporter family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • having nucleotide-sugar transporter activity
  • taking part in the synthesis of heparan sulfate by regulating the level of UDP-GlcNAc, a donor substrate for the heparan sulfate synthases
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    ATP binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS