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FLASH GENE

Symbol

SLC30A7

contributors: npt/ - updated : 31-12-2003

HGNC name	solute carrier family 30 (zinc transporter), member 7
HGNC id	19306

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	1p21.2      Physical location : 101.361.631 - 101.447.311
Synonym name	zinc transporter ZnT-7
	zinc transporter like 2
Synonym symbol(s)	ZNT7, ZnTL2, DKFZp686M0368

DNA

TYPE	functioning gene
STRUCTURE	85.68 kb     12 Exon(s)

Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001144884 12 - 7918 NP_001138356 - 376 - - NM_133496 11 - 8232 NP_598003 - 376 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver         Nervous brain diencephalon amygdala     Respiratory lung         Urinary kidney         Visual eye anterior segment

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	six transmembrane domains and
	a histidine-rich loop between transmembrane domains IV and V.

HOMOLOGY

Homologene

FAMILY	cation diffusion facilitator (CDF) transporter family
	SLC30A subfamily
	subfamily

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,Golgi
	intracellular,cytoplasm,cytosolic,vesicle

basic FUNCTION	having cation transporter activity
	facilitating zinc transport from the cytoplasm into the Golgi apparatus

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS