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FLASH GENE
Symbol SLC25A28 contributors: - updated : 21-10-2004
HGNC name solute carrier family 25, member 28
HGNC id 23472
Location 10q24      Physical location : 101.370.274 - 101.380.221
Synonym name
  • putative mitochondrial solute carrier
  • hypothetical protein NPD016
  • Synonym symbol(s) MRS3/4, NPD016
    DNA
    TYPE functioning gene
    STRUCTURE 9.00 kb     4 Exon(s)
    MAPPING cloned Y linked N status provisional
    Physical map
    C10orf33 10q24.2 chromosome 10 open reading frame 33 HPS1 10q23.1-q23.3 Hermansky-Pudlak syndrome 1 HPSE2 10q23-q24 heparanase 2 CNNM1 10q24.33 cyclin M1 GOT1 10q24 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) NKX2-3 10q24.33 NK2 transcription factor related, locus 3 (Drosophila) SLC25A28 10q24 solute carrier family 25, member 28 LALP1 10q23-q24 solute carrier family 25, member 28 COX15 10q24 COX15 homolog, cytochrome c oxidase assembly protein (yeast) CGI-32 10q24.31 CGI-32 protein ABCC2 10q24 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 KIAA1010 10q25.1 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 CPN1 10q24.31 carboxypeptidase N, polypeptide 1, 50kD KEO4 CHUK 10q24-q25 conserved helix-loop-helix ubiquitous kinase FLJ10998 10q24.31 hypothetical protein FLJ10998 MGC10120 10q24.31 hypothetical protein MGC10120 PKD2L1 10q24-q25 polycystic kidney disease 2-like 1 SCD 10q23-q24 stearoyl-CoA desaturase (delta-9-desaturase) LOC90271 10q24.31 hypothetical protein LOC90271 WNT8B 10q24 wingless-type MMTV integration site family, member 8B SEC31L2 10q24.32 SEC31-like 2 (S. cerevisiae) NDUFB8 10q23.2-q23.33 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa HIF1AN 10q24 hypoxia-inducible factor 1, alpha subunit inhibitor PAX2 10q22.1-q24.3 paired box gene 2
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver   highly
    Endocrinepancreas    
    Nervousbrain    
    Reproductivefemale systemplacenta   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    six transmembrane domains
    HOMOLOGY
    interspecies homolog to murine Mrs3/4-pending
    homolog to rattus LOC293957
    Homologene
    FAMILY mitochondrial carrier protein family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    text integral membrane protein
    basic FUNCTION
  • may be involved in mitochondrial transport
  • can substitute its yeast homologs (MRS3 and MRS4) and restore cell growth
  • may have a role in RNA splicing
  • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS mitochondrial transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS