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FLASH GENE
Symbol SLC25A27 contributors: np - updated : 06-01-2004
HGNC name solute carrier family 25, member 27
HGNC id 21065
Location 6p12.3      Physical location : 46.620.678 - 46.645.925
Synonym name
  • uncoupling protein 4
  • mitochondrial uncoupling protein 4
    • Synonym symbol(s) UCP4, FLJ33552, RP11-446F17.2, UNQ772/PRO1566
    DNA
    TYPE functioning gene
    STRUCTURE 24.00 kb     9 Exon(s)
    MAPPING cloned Y linked N status provisional
    Physical map
    SUPT3H 6p21.3-p21.1 suppressor of Ty 3 homolog (S. cerevisiae) RUNX2 6p21 runt-related transcription factor 2 CLIC5 6p12.1-21.1 chloride intracellular channel 5 ENPP4 6p21.1-p11.2 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function) ENPP5 6p21.1-p11.2 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) ACTGP9 6p21.1 actin, gamma pseudogene 9 DSCR1L1 6p21-p11 Down syndrome critical region gene 1-like 1 LOC340211 6p21.1 similar to LINE-1 REVERSE TRANSCRIPTASE HOMOLOG CYP39A1 6p21.1-p11.2 cytochrome P450, family 39, subfamily A, polypeptide 1 SLC25A27 6p12.3 solute carrier family 25, member 27 TDRD6 6p21.1 tudor domain containing 6 PLA2G7 6p21.2-p12 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) LOC389394 6 similar to hypothetical protein DKFZp434D2328 MEP1A 6p21.2-p21.1 meprin A, alpha (PABA peptide hydrolase) GPR116 6p12.3 G protein-coupled receptor 116 GPR110 6p21.1 G protein-coupled receptor 110 FLJ22684 6p21.1 hypothetical protein FLJ22684 TNFRSF21 6p21.1-12.2 tumor necrosis factor receptor superfamily, member 21 CD2AP 6p12 CD2-associated protein GPR111 6p12.3 G protein-coupled receptor 111 GPR115 6p12.3 G protein-coupled receptor 115 C6orf138 6p12.3 chromosome 6 open reading frame 138 LOC389395 6 similar to heterogeneous nuclear ribonucleoprotein A3 RBMXP1 6p12.3 RNA binding motif protein, X chromosome pseudogene 1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 2959 36 323 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrainforebraincerebral lobefrontal 
     braindiencephalon   
    Urinarykidney    
    Visualeyeretina   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelial    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text brain
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • mitochondrial substrate carrier family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • facilitating the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane
  • involved in thermoregulatory heat production
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by acute cold exposure
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY mitochondrial uncoupling proteins family
    CATEGORY
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by acute cold exposure
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS