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FLASH GENE
Symbol SLC25A21 contributors: - updated : 29-06-2004
HGNC name solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
HGNC id 14411
Location 14q11.2      Physical location : 37.147.125 - 37.641.865
Synonym name oxodicarboxylate carrier
Synonym symbol(s) ODC1
DNA
TYPE functioning gene
STRUCTURE 492.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
PSMA6 14q13 proteasome (prosome, macropain) subunit, alpha type, 6 LOC122589 14q13.2 similar to 60S acidic ribosomal protein P0 (L10E) NFKBIA 14q13 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha DNAJC8P1 14 DnaJ (Hsp40) homolog, subfamily C, member 8 pseudogene 1 LOC387983 14 LOC387983 LOC390467 14 similar to 40S RIBOSOMAL PROTEIN S3A (V-FOS TRANSFORMATION EFFECTOR PROTEIN) LOC122592 14q13.2 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) INSM2 14q13.1 insulinoma-associated 2 LOC387984 14 similar to GARNL1 protein GARNL1 14q13.2 GTPase activating RANGAP domain-like 1 LOC341835 14q13.2 similar to glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 NUTF2P2 14 nuclear transport factor 2 pseudogene 2 BRMS1L 14q13.2 breast cancer metastasis-suppressor 1-like LOC390468 14 similar to Plasmodium falciparum trophozoite antigen r45-like protein LOC390469 14 similar to interleukin enhancer binding factor 2 MBIP 14q13 similar to interleukin enhancer binding factor 2 LOC387985 14 hypothetical gene supported by AY102071 TITF1 14q13.1-q13.2 thyroid transcription factor 1 PHKBP2 14q13.2 phosphorylase kinase, beta pseudogene 2 NKX2-8 14q13.1-p13.2 NK2 transcription factor related, locus 8 (Drosophila) PAX9 14q12-q13.1 paired box gene 9 SLC25A21 14q11.2 solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 MIPOL1 14q13.3 solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 FOXA1 14q12-q13 forkhead box A1 TTC6 14q13.2 tetratricopeptide repeat domain 6 LOC387986 14 LOC387986
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
three tandemly repeated mitochondrial carrier protein domains
HOMOLOGY
interspecies homolog to yeast odc
Homologene
FAMILY solute carrier family 25,mitochondrial
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
basic FUNCTION
  • transport of 2 oxoadipate and 2 oxoglutarate by an exchange mechanism across the inner membrane of mitochondria
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS active transport
    PATHWAY
    metabolism aminoacid
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS