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FLASH GENE
Symbol SLC25A2 contributors: mct/ - updated : 20-08-2007
HGNC name solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
HGNC id 22921
Location 5q31.3      Physical location : 140.682.196 - 140.683.612
Synonym name
  • ornithine transporter 2
  • mitochondrial ornithine transporter 2
  • Synonym symbol(s) ORNT2, ORC2, MGC119153, MGC119151
    DNA
    TYPE functioning gene
    STRUCTURE 1.42 kb     1 Exon(s)    single Copie(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1417 - 301 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Endocrinepancreas    
    Reproductivemale systemtestis  highly Homo sapiens
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three solcar repeats
  • two predicted transmembrane alpha helices separated by a hydrophilic segment
  • HOMOLOGY
    intraspecies paralog to ORNT1
    Homologene
    FAMILY
  • mitochondrial carrier family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    basic FUNCTION
  • mediating the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS mitochondrial transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS