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FLASH GENE
Symbol SLC22A9 contributors: mct - updated : 04-05-2011
HGNC name solute carrier family 22 (organic anion/cation transporter), member 9
HGNC id 16261
Location 11q13.1      Physical location : 63.137.260 - 63.177.710
Synonym name
  • organic anion transporter 7
  • Synonym symbol(s) OAT4, FLJ23666, HOAT4, OAT7, UST3H, ust3
    DNA
    TYPE functioning gene
    STRUCTURE 40.47 kb     10 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence Promoter
    Binding site
    text structure
  • one HNF-1A binding elements in the proximal promoter (
  • MAPPING cloned Y linked N status provisional
    Physical map
    GNG3 11p11 guanine nucleotide binding protein (G protein), gamma 3 DKFZp762N1910 11q12.3 hypothetical protein DKFZp762N1910 MGC29649 11q12.3 hypothetical protein MGC29649 ZBTB3 11q12.3 zinc finger and BTB domain containing 3 POLR2G 11q13.1 polymerase (RNA) II (DNA directed) polypeptide G TAF6L 11q13.1 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa LOC387617 11 hypothetical gene supported by NM_018336 LOC374395 11q12.3 similar to RIKEN cDNA 1810059G22 NXF1 11q12-q13 nuclear RNA export factor 1 STX5A 11cen-q12.1 syntaxin 5A FLJ10439 11q12.3 hypothetical protein FLJ10439 SLC3A2 11q12-q22 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 CHRM1 11q12-q13 cholinergic receptor, muscarinic 1 SLC22A6 11q13.1-q13.2 solute carrier family 22 (organic anion transporter), member 6 SLC22A8 11q11.7 solute carrier family 22 (organic anion transporter), member 8 LOC390207 11 similar to Tubulin alpha-4 chain (Alpha-tubulin 4) LOC390208 11 similar to ribosomal protein L29 MGC34821 11q12.3 hypothetical protein MGC34821 LOC387601  putative UST1-like organic anion transporter CCND2P 11q13 cyclin D2 pseudogene LOC387775 11 similar to organic anion transporter 6 SLC22A9 11q13.1 solute carrier family 22 (organic anion/cation transporter), member 9 HRLP5 11q13.2 H-rev107-like protein 5 LGALS12 11q13 lectin, galactoside-binding, soluble, 12 (galectin 12) TMSL5 11 thymosin-like 5 RARRES3 11q23 retinoic acid receptor responder (tazarotene induced) 3 HRASLS2 11q13.1 HRAS-like suppressor 2 HRASLS3 11q13.1 HRAS-like suppressor 3 LOC283241 11q13.1 hypothetical protein LOC283241 DKFZP564J0863 11q13.1 DKFZP564J0863 protein RTN3 11q13 reticulon 3 LOC144097 11q13.1 hypothetical protein BC007540 MARK2 11q12-q13 MAP/microtubule affinity-regulating kinase 2 LOC283248 11q13.1 hypothetical protein LOC283248 FLJ13848 11q13.1 hypothetical protein FLJ13848 COX8 11q13.1 cytochrome c oxidase subunit VIII OTUB1 11q13.1 OTU domain, ubiquitin aldehyde binding 1 LRP16 11q11 LRP16 protein
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 2327 - 553 - 2001 11327718
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • twelve transmembrane domains (12TM), with cytoplasmic N and C termini
  • one nucleotide (ATP/GTP) binding site motif
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • uptake of fetal derived steroid sulfatin by trophoblast
  • mediated Na(+)-independent, high-affinity transport of sulfate-conjugated steroids, estrone sulfate, and dehydroepiandrosterone sulfate
  • involved in the transport of anionic substances such as sulfate-conjugates in exchange for butyrate in hepatocytes
  • with SLC22A12, are key transporters in renal reabsorption of perfluorocarboxylates
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • transactivated by hepatocyte nuclear factor-1 (HNF-1A) (
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS