basic FUNCTION
| Na+ (and K+) dependent glutamate transporter, accepting as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids |
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plays a key role in Gln transport controlling lung cancer cells metabolism, growth, and survival  |
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ERVW1 and its receptor SLC1A45 are present in human gametes and localization and temporal appearance is consistent with a possible role in fusion between oocyte and sperm  |
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is an important transporter of glutamine various cancer cells  |
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N-linked glycosylation of SLC1A5 (ASCT2) transporter is critical for trafficking to membrane  |
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involved in balancing the intracellular amino acid pool  |
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plasma membrane transporter, responsible for mediating Na- dependent antiport of neutral amino acids  |
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is responsible for the uptake of glutamine into cells, a major source of cellular energy and a key regulator of mammalian target of rapamycin (MTOR) activation  |
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plays an important role in esophageal cancer  |