Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLC17A9 contributors: mct/pgu - updated : 08-09-2010
HGNC name solute carrier family 17, member 9
HGNC id 16192
Location 20q13.33      Physical location : 61.583.998 - 61.599.941
Synonym name
  • chromosome 20 open reading frame 59
  • vesicular nucleotide transporter SLC17A9
  • Synonym symbol(s) FLJ23412, C20orf59
    DNA
    TYPE functioning gene
    STRUCTURE 15.95 kb     13 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    13 - 2612 47.3 436 - 2008 18375752
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrainlimbic systemhippocampus highly
     brainforebraincerebral cortex highly
     braindiencephalonthalamus highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Nervouscentral  highly
    Nervousperipherous  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • 12 putative transmembrane domains
  • HOMOLOGY
    Homologene
    FAMILY
  • major facilitator superfamily
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • vesicular nucleotide transporter and should lead to the elucidation of the molecular mechanism of ATP secretion in purinergic signal transmission
  • SLC17A9-dependent vesicular exocytosis in ATP release and T cell activation
  • involved in vesicular storage of ATP and exocytosis of ATP, and plays a critical role in both vesicular exocytosis of ATP and TCR signaling during T cell activation
  • contributed to ATP vesicle formation and regulated ATP release
  • existence of an SLC17A9-dependent ATP-enriched vesicular pool in biliary epithelium that undergoes regulated exocytosis to initiate purinergic signaling
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS