Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLC12A9 contributors: mct/npt - updated : 06-10-2009
HGNC name solute carrier family 12 (potassium/chloride transporters), member 9
HGNC id 17435
Location 7q22.1      Physical location : 100.450.357 - 100.464.633
Synonym name
  • cation-chloride cotransporter-interacting protein 1
  • CCC-interacting protein 1
  • potassium-chloride transporter 9
    • Synonym symbol(s) CIP1, WO3.3, CCC6, FLJ46905
    DNA
    TYPE functioning gene
    STRUCTURE 14.28 kb     14 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    14 - 3308 - 914 - Caron (2000)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • 12-transmembrane domain (TM) region,
  • two N-linked glycosylation sites between TM(5) and TM(6), and
  • a large intracellular loop at the C-terminus containing protein kinase C phosphorylation sites (Wenz 2009)
    • HOMOLOGY
    interspecies homolog to C .elegans k02a2.3.
    Homologene
    FAMILY
  • SLC12A transporter family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be modulating cation-chloride cotransporter (CCC)activity or kinetics through heterodimer formation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • potent activator of SLC12A5 (activates SLC12A5 by heteromer formation)(Wenz 2009)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS