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FLASH GENE
Symbol SKOR2 contributors: mct - updated : 19-03-2009
HGNC name SKI family transcriptional corepressor 2
HGNC id 32695
Location 18q21.1      Physical location : -
Synonym name
  • ladybird homeobox corepressor 1-like protein
  • functional smad suppressing element 18
  • LBX1 corepressor 1-like protein
  • Synonym symbol(s) CORL2, FUSSEL18
    DNA
    TYPE functioning gene
    STRUCTURE 29.26 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain     Homo sapiens
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Nervouscentral  specific Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
  • Ski/Sno proto-oncoproteins family
  • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • molecular regulator of BMP signaling
  • Smad-binding protein with a highly restricted expression pattern within the nervous system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with SMAD2, SMAD3 and SMAD4 and has an inhibitory activity on TGF-beta signaling
  • cell & other
    REGULATION
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
  • Ski/Sno proto-oncoproteins family
  • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • molecular regulator of BMP signaling
  • Smad-binding protein with a highly restricted expression pattern within the nervous system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with SMAD2, SMAD3 and SMAD4 and has an inhibitory activity on TGF-beta signaling
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker a specific marker for PCs in the cerebellum from their emergence until the adult stage
    Therapy target
    ANIMAL & CELL MODELS