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FLASH GENE
Symbol SIPA1L2 contributors: - updated : 10-06-2005
HGNC name signal-induced proliferation-associated 1 like 2
HGNC id 23800
Location 1q42.2      Physical location : 232.533.713 - 232.651.243
Synonym symbol(s) KIAA1389
DNA
TYPE functioning gene
STRUCTURE 116.00 kb     20 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
ACTA1 1q42.13-q42.2 actin, alpha 1, skeletal muscle NUP133 1q42.13 nucleoporin 133kDa ABCB10 1q42 ATP-binding cassette, sub-family B (MDR/TAP), member 10 TAF5L 1q42.13 TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa KIAA0133 1q42.13 TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa LOC391177 1 similar to HMG-1 LOC388752 1 LOC388752 GALNT2 1q41-q42 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) PGBD5 1q42.13 piggyBac transposable element derived 5 COG2 1q41 component of oligomeric golgi complex 2 AGT 1q42-q43 angiotensinogen (serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8) CAPN9 1q42.11-q42.3 calpain 9 (nCL-4) FLJ14525 1q42.13-q43 hypothetical protein FLJ14525 TTC13 1q42.2 tetratricopeptide repeat domain 13 ARV1 1q42.2 likely ortholog of yeast ARV1 MGC15887 1q42.2 hypothetical gene supported by BC009447 FLJ30430 1q42.2 hypothetical protein FLJ30430 DKFZp547B1713 1q42.2 hypothetical protein DKFZp547B1713 GNPAT 1q42.11-q42.3 glyceronephosphate O-acyltransferase EXOC8 1q42.2 exocyst complex component 8 DKFZP547N043 1q42.12-q43 hypothetical protein DKFZp547N043 EGLN1 1q42.1 egl nine homolog 1 (C. elegans) TSNAX 1q42.1 translin-associated factor X DISC1 1q42.1 disrupted in schizophrenia 1 SIPA1L2 1q42.2 signal-induced proliferation-associated 1 like 2 KIAA1383 1q42.2 KIAA1383 protein MGC13186 1q42.2 hypothetical protein MGC13186 FLJ11383 1q42.2 hypothetical protein FLJ11383 LOC148995 1q42.2 similar to 40S ribosomal protein S7 (S8) KIAA1804 1q42 mixed lineage kinase 4 KCNK1 1q42-q43 potassium channel, subfamily K, member 1 SLC35F3 1q42.3 solute carrier family 35, member F3 LOC148640 1q42.3 similar to ribosomal protein S15 LOC388753 1 similar to RIKEN cDNA 1810063B05 TARBP1 1q42.3 TAR (HIV) RNA binding protein 1 IRF2BP2 1q42.3 interferon regulatory factor 2 binding protein 2 LOC284527 1q42.3 hypothetical gene supported by BC016972 TOMM20 1q42 hypothetical gene supported by BC016972 KIAA0117 1q42.3 KIAA0117 protein RBP1L1 1q42.1-q43 retinoblastoma binding protein 1-like 1 GGPS1 1q43 geranylgeranyl diphosphate synthase 1 TBCE 1q42.3 tubulin-specific chaperone e MGC39558 1q42.3 hypothetical protein MGC39558
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
 mouthtongue  moderately
Reproductivemale systemtestis  moderately
Respiratorylung   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a PDZ (DHR) domain
  • a Rap-GAP domain
  • HOMOLOGY
    interspecies ortholog to murine Sipa1l2
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • acting as a GTPase activator
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS