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FLASH GENE
Symbol SIPA1L2 contributors: - updated : 10-06-2005
HGNC name signal-induced proliferation-associated 1 like 2
HGNC id 23800
Location 1q42.2      Physical location : 232.533.713 - 232.651.243
Synonym symbol(s) KIAA1389
DNA
TYPE functioning gene
STRUCTURE 116.00 kb     20 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
 mouthtongue  moderately
Reproductivemale systemtestis  moderately
Respiratorylung   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a PDZ (DHR) domain
  • a Rap-GAP domain
  • HOMOLOGY
    interspecies ortholog to murine Sipa1l2
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • acting as a GTPase activator
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS