Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SI contributors: mct - updated : 04-09-2018
HGNC name sucrase-isomaltase
HGNC id 10856
Corresponding disease
CSID sucrase-isomaltase deficiency
Location 3q26.1      Physical location : 164.696.686 - 164.796.283
Synonym name
  • oligosaccharide alpha-1,6-glucosidase
    • Synonym symbol(s) MGC131621, MGC131622
    EC.number 3.2.1.10, 3.2.1.48
    DNA
    TYPE functioning gene
    STRUCTURE 99.00 kb     48 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - D3S20 /D3S21 - D3S47 - D3S14 , D3S196 - SI - qter
    Authors LDB (99)
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon  
     intestinesmall intestine   
    Endocrinethyroid    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    		a p-type (trefoil) domain
    HOMOLOGY
    Homologene
    FAMILY glycosyl hydrolase 31 family
    CATEGORY enzyme , unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • sucrase-isomaltase, alpha D-glucosidase from intestinal mucosa that hydrolyzes sucrose and isomaltase
  • protein of the small intestine brush-border membrane responsible for catalyzing the hydrolysis of dietary sucrose and some of the products of starch digestion
  • playing an important role in the final stage of carbohydrate digestion
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CSID
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS