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FLASH GENE
Symbol SHB contributors: - updated : 25-04-2005
HGNC name SHB (Src homology 2 domain containing) adaptor protein B
HGNC id 10838
Location 9p12-p11      Physical location : 37.915.895 - 38.069.210
DNA
TYPE functioning gene
STRUCTURE 149.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
LOC392313 9 similar to olfactory receptor RECK 9p13-p12 reversion-inducing-cysteine-rich protein with kazal motifs C9orf19 9p12-p13 chromosome 9 open reading frame 19 CCIN 9p13-p12 calicin CLTA 9p13-p12 clathrin, light polypeptide (Lca) GNE 9p13-p12 clathrin, light polypeptide (Lca) LOC392314 9 similar to high mobility group protein homolog HMG4 RNF38 9p13-p12 ring finger protein 38 MRPS21P4 9p13.1 mitochondrial ribosomal protein S21 pseudogene 4 MELK 9p11.2 maternal embryonic leucine zipper kinase PAX5 9p13 paired box gene 5 (B-cell lineage specific activator protein) LOC389720 9 LOC389720 LOC392315 9 similar to 60S ribosomal protein L32 FLJ22611 GRHPR 9q11.2-q12 glyoxylate reductase/hydroxypyruvate reductase ZBTB5 9p13.1 zinc finger and BTB domain containing 5 LOC158237 9p13.1 similar to potassium channel tetramerisation domain containing 9 PAF53 9p13.1 RNA polymerase I associated factor 53 FBXO10 9p12 F-box only protein 10 LOC389721 9 similar to RAB1B, member RAS oncogene family; small GTP-binding protein FRMPD1 9p13.1 FERM and PDZ domain containing 1 FLJ31455 9p13.1 hypothetical protein FLJ31455 RRP40 9p11 exosome component Rrp40 MRPS10P5 9p12 exosome component Rrp40 MGC10765 9p13.1 hypothetical protein MGC10765 MCART1 9p13.3-p12 mitochondrial carrier triple repeat 1 SHB 9p12-p11 SHB (Src homology 2 domain containing) adaptor protein B ALDH1B1 9p13 aldehyde dehydrogenase 1 family, member B1 LOC347252 9p12 similar to bA113O24.1 (similar to insulin-like growth factor binding protein) LOC340501 9p12 similar to transcription elongation factor IIS - mouse LOC340502 9p12 similar to GAS2-related protein isoform beta FLJ35740 9p12 FLJ35740 protein LOC392316 9 similar to SNAG1 CASPR3 9p12 cell recognition molecule CASPR3 LOC392317 9 similar to SPF45 protein LOC389722 9 similar to cell recognition molecule CASPR3 isoform 1
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Gustatory (taste)tongue    
Reproductivefemale systemovary   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one sh3 domain
  • one SH2 domain (maybe signal transduction)
  • HOMOLOGY
    Homologene
    FAMILY
  • tyr protein kinase family
  • abl subfamily
  • CATEGORY adaptor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION SHB adaptor protein
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS